Effect of optical
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Effect of optical myopia-control interventions on peripheral vision
Papadogiannis P1
, Börjeson C1
, Lundström L1
1-KTH Royal Institute Of Technology
Purpose:
Animal studies suggest that the peripheral retina has an important role in the regulation of
eye growth. Different optical interventions for myopia control aim to manipulate the peripheral
image in order to slow the progression of myopia, but it is not yet known what the peripheral effect
of these interventions is compared to each other. This study investigates the similarities and
dissimilarities of different optical interventions in their effect on peripheral vision with the aim to
better understand their treatment properties.
Methods:
Peripheral (20° nasal visual field) low-contrast (10%) resolution acuity of 2 myopes was
evaluated by a two-alternative forced-choice paradigm with four optical myopia control
interventions: a) spectacles with horizontal progressive addition (Perifocal from ArtOptica), b)
spectacles with highly aspherical lenslets (Stellest from Essilor), c) spectacles with defocus
incorporated multiple segments (MiyoSmart from Hoya), and d) multifocal soft contact lenses
(MiSight from Cooper Vision). The peripheral acuity thresholds were compared with those of normal
monofocal spectacles (control). All measurements were repeated three times and the average
thresholds in logMAR as well as the differences from the control were calculated (intervention
threshold minus control threshold).
Results:
The differences in thresholds from the control case for subject 1 were a) 0.005 logMAR for
Perifocal, b) -0.004 logMAR for Stellest, c) 0.019 logMAR for MiyoSmart and d) 0.232 logMAR for
Misight. For subject 2 the differences in thresholds were a) 0.038 logMAR for Perifocal, b) 0.076
logMAR for Stellest, c) 0.085 logMAR for MiyoSmart and d) 0.117 for MiSight.
Conclusion:
In both subjects, the MiSight intervention reduced peripheral vision more, followed by
MiyoSmart. Thus, we can conclude that although all four interventions have been reported to have
similar myopia control efficacy, there is a large difference in how much they reduce the retinal
contrast. Furthermore, there is substantial variation on individual level. Knowledge of the contrast
reduction caused by the intervention in the individual eye may provide cues on how to optimize the
treatment effect. It should also be balanced against safety, since large contrast reductions in the
periphery hamper daily tasks involving peripheral vision such as detection, orientation, and
locomotion.